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Clinical Window is main sponsor for this concise, textbook style website of anaesthesiology

History of anesthesiology in 40 milestone texts.
More medical history coming later!

This is short historic account of milestones in anesthesiology. Please click any of the 40 pictures to see the story behind it:

  The development of intratracheal insufflation with positive pressure 1871-1910.
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    Pierre Oré reintroduced intravenous anesthesia in 1875 and Emile Fischer synthesized a drug of lasting value in 1903. More...
         
  Carl Koller and Leonard Corning, the clinical introduction of cocaine as local anesthetics 1884 -1885.
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    The use of cold as an anesthetic agent from Avicenna to Richardson and beyond. More...
         
  Gardner Colton and Paul Bert both instrumental in the acceptance of nitrous oxide anesthesia 1862-1878.
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    Claude Bernard studied inhalations anesthetics and the alkaloids and suggested the use of mixed anesthesia 1864. More...
         
  E Marey invented equipment and graphical recording techniques for studies in science and medicine. More...     Clover invented means to administer anesthetic gases and stressed the importance of vital signs monitoring. More...
         
  John Snow placed the administration of ether and chloroform on a scientific basis 1858.
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    Simpson pioneered the use of chloroform in midwifery, Queen Victoria becoming a celebrated patient in 1853. More...
         
  Flourens and Longet were the first to study the effects of ether and chloroform on the central nervous system.
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    Surgeons J C Warren and H J Bigelow and the first announcement of the successful ether anesthesia. More...
         
  Massachusetts General Hospital and the operating theater where ether anesthesia was introduced, as seen 1847.
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    Charles Jackson played a key role in the successful demonstration of ether anesthesia on October 16 1846.
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  William Morton demonstrated ether anesthesia at the Massachusetts General Hospital on October 16 1846.
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    Crawford Long a general practitioner in Georgia who was first to use ether for surgical anesthesia, in 1842.
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  Henry Hickman and Horace Wells, young men who tried in vain to establish the practice of inhalation anesthesia.
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    Liebig, Souberain and Guthrie discovered chloroform in 1831, Dumas determined its proper formula in 1834.
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  Serturner isolated morphine, the active part of opium in 1805 and Magendie introduced it into medical practice in 1822.
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    Hanaoka Seishu Japanese physician who produced general anesthesia using a recipe based on mandragora 1805
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  In 1830, nitrous oxide (laughing gas) was only suggested for other uses than medical.
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    Sir Humphry Davy discovered the anesthetic properties of nitrous oxide and suggested its use in surgery 1800.
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  Joseph Priestley discovered many important gases including nitrous oxide, which he first prepared in 1772. More...     Matthew Turner a surgeon in Liverpool who manufactured ether and used it to treat many ailments 1761.
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  Occult methods of healing and pain relief – from shamanism to mesmerism 16000 BC to 1784 AD.
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    Sir Christopher Wren, famous architect who performed the first intravenous anesthesia around 1656.
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  The development of the understanding of what a gas is, by van Helmont, Boyle and Bernoulli 1648-1738
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    William Shakespeare refers to soporific agents in his plays Othello (1604) and Anthony and Cleopatra (1606)
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  Paracelsus who discovered and described the anesthetic effects of ether, around 1540
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    Raymond Lull, Valerius Cordus and Antoine Baume and the discovery and preparation of ether 1275-1757
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  Heinrich von Pfolsprundt gave an early account of the use of the soporific sponge in European surgery 1460
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    The famed surgeons Albucasis and Ibn Zuhr used the soporific sponge for inhalation anesthesia 1000-1100 AD
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  Avicenna, Islamic philosopher, the Prince of Physicians, who wrote the Cannon of Medicine about 1000 AD. More...     Greek physician Dioscorides, wrote a comprehensive treatise on medical plants, De Materia Medica, 77 AD. More...
         
  Cornelius Celsus described in some detail the preparation of pills that could alleviate pain about 25 AD. More...     The Greek philosopher Theophrastus, the founder of botany, wrote on opium and other plants around 300 BC. More...
         
  Babylonian – Assyrian prescriptions for pain relief in cuneiform writing on clay tablets about 1000 BC. More...     Queen Nefertiti offering the mandrake (mandragora) plant to her husband, Pharaoh Akhenaten, around 1350 BC. More...
         
  According to the Ebers Papyrus, a 110-page medical papyri, henbane was know in ancient Egypt about 1550 BC. More...     The Second Emperor of China, Shen Nung, who described the hemp plant (cannabis) around 2700 BC. More...

Last updated: 31 January 2006
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